I have tried many different ergonomic mice all with mixed results. I finder the larger ergonomic mice push my shoulder to all the work which i find really awkward. When using my normal mouse I use my fingers to move the mouse during normal pc use and when gaming but twisting my hand to be flat on the desk causes some RSI issues and think may of been leading to carpal tunnel syndrome. I bought the DXT Mouse because I wanted an ergonomic mouse to keep the accuracy while reducing the hand flat on the desk. Its really worked and reduces my RSI and I feel is the best ergonomic mouse for carpal tunnel pain.